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Qwen 2.5 Quantization: Performance by Format & GPU

Performance comparison of Qwen 2.5 7B and 72B across GPTQ, AWQ, GGUF, and FP16 on multiple GPUs, with quality benchmarks and format recommendations.

Qwen 2.5 Quantisation Overview

Qwen 2.5 is available in sizes from 0.5B to 72B parameters, and quantisation is the key to running these models cost-effectively on a dedicated GPU server. This guide benchmarks the 7B and 72B variants across GPTQ, AWQ, and GGUF formats to help you pick the right combination for your hardware and quality requirements.

For baseline hosting options see our Qwen hosting page. For VRAM requirements at different context lengths, check the Qwen 2.5 context length VRAM guide.

Qwen 2.5 7B Speed by Format

Benchmarks run on GigaGPU servers with 512 input tokens and 256 output tokens. GPTQ and AWQ use vLLM, GGUF uses llama.cpp with full GPU offload.

GPUFP16 (tok/s)GPTQ 4-bit (tok/s)AWQ 4-bit (tok/s)GGUF Q4_K_M (tok/s)
RTX 4060 (8 GB)N/A262420
RTX 4060 Ti (16 GB)32464336
RTX 3090 (24 GB)43605748
RTX 5080 (16 GB)68908672
RTX 5090 (32 GB)95128122100

Performance patterns mirror other 7B models: GPTQ leads by 3-5%, AWQ sits close behind, and GGUF lags by 20-25%. See our LLaMA 3 8B speed comparison for a direct cross-model benchmark.

Qwen 2.5 72B Speed by Format

The 72B model requires multi-GPU setups at all precision levels. Tensor parallelism via vLLM is used for all GPU configurations.

GPU ConfigTotal VRAMFP16 (tok/s)GPTQ 4-bit (tok/s)AWQ 4-bit (tok/s)
2x RTX 309048 GBN/A1211
2x RTX 509064 GBN/A2221
4x RTX 309096 GBN/A1817
2x RTX 6000 Pro 96 GB160 GB203230
4x RTX 6000 Pro 96 GB320 GB354846

INT4 quantisation makes 72B accessible on consumer hardware — 2x RTX 5090 (64 GB) delivers 22 tok/s with GPTQ. For deployment strategies, see our model sharding guide.

Quality Comparison

Quality measured as percentage of FP16 baseline scores across coding, reasoning, and general benchmarks.

ModelFormatCodingReasoningGeneral
7BGPTQ 4-bit95%96%97%
7BAWQ 4-bit96%97%97%
7BGGUF Q4_K_M96%97%98%
72BGPTQ 4-bit96%97%98%
72BAWQ 4-bit97%97%98%

The 72B model retains quality better than the 7B under quantisation — larger models have more redundancy in their weight matrices. AWQ edges out GPTQ on quality by 1-2% across all model sizes.

Format Recommendations

  • Qwen 2.5 7B on single GPU: use GPTQ 4-bit for speed or AWQ 4-bit for quality. Both fit on 8 GB GPUs with room for 8K context.
  • Qwen 2.5 72B on multi-GPU: AWQ 4-bit recommended — quality preservation matters more at this scale, and speed difference vs GPTQ is minimal.
  • High-concurrency serving: GPTQ 4-bit with continuous batching maximises throughput per GPU dollar.
  • CPU/GPU hybrid: GGUF for the 7B model only — the 72B is impractical for partial offloading due to size.
  • Quality-critical tasks: INT8 or FP16 if VRAM permits. See FP16 vs INT8 vs INT4 for trade-off details.

For throughput tuning, review our vLLM optimisation guide. Browse all benchmarks in the Benchmarks category.

Conclusion

Qwen 2.5 quantises well at both the 7B and 72B scale. GPTQ 4-bit delivers peak speed, AWQ 4-bit offers marginally better quality, and both cut VRAM by 70%+ compared to FP16. For production deployments, match the format to your serving stack — vLLM users should prefer GPTQ or AWQ, while llama.cpp users should stick with GGUF. Check our tokens per second benchmark hub for broader comparisons.

Run Qwen 2.5 at Any Scale

From single-GPU 7B deployments to multi-GPU 72B clusters. Pre-configured for vLLM with GPTQ and AWQ support.

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