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Multi-Server AI Inference Load Balancing: Patterns and Pitfalls

Once you outgrow a single GPU server, load balancing becomes the new problem. Round-robin? Sticky sessions? KV-cache aware? Here is the practical guide.

One GPU server has its capacity ceiling. The next problem is splitting traffic across multiple servers without losing prefix-cache hits or breaking latency SLAs.

TL;DR

For 2-3 GPU servers behind a load balancer: LiteLLM with latency-based routing. For 4+ servers with prefix caching: session-affinity routing by user_id. For 10+ servers, consider Ray Serve or Triton.

When to scale out

  • Single server queue depth consistently > 100
  • p99 TTFT consistently > 1 s
  • You can’t fit on the largest available card
  • You need redundancy for SLA

Load balancing patterns

  1. Round-robin: simplest. Loses prefix cache hits across servers.
  2. Latency-based: route to fastest-responding. LiteLLM does this.
  3. Least connections: route to server with fewest active sequences.
  4. Session affinity: hash user_id → server. Preserves prefix cache.
  5. KV-cache aware: route based on which server already has the prompt prefix cached. Optimal but complex.

KV-cache-aware routing

vLLM exposes /v1/cache_status showing which prefixes are cached. A custom router can hash the prompt prefix and route to the server that already has it.

Net effect: 30-50% better cache hit rate vs round-robin. Worth the complexity at 4+ server scale.

Verdict

Start with LiteLLM latency-based routing. Move to session affinity at ~5 servers. Move to KV-cache-aware only when justified by metrics.

Bottom line

Multi-server LLM serving is mostly an exercise in preserving prefix cache hit rate. See monitoring guide.

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