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Caching Strategies for LLM Inference: Beyond Prefix Caching

Five caching layers that reduce LLM cost — prompt cache, response cache, embedding cache, retrieval cache, KV cache. When each one helps.

Table of Contents

  1. Five caching layers
  2. Verdict

vLLM's prefix caching is one of five caching layers worth using.

TL;DR

Layered caching: 1) Prefix/KV cache (vLLM, free), 2) Response cache (Redis, exact prompt match), 3) Semantic cache (Redis + embeddings, similar prompt), 4) Embedding cache (avoid re-embedding), 5) Retrieval cache (Qdrant query results).

Five caching layers

  1. KV / prefix cache (vLLM): reuses prompt prefix KV state — see prefix caching
  2. Response cache: Redis keyed on prompt hash → cached response (exact match only)
  3. Semantic cache: embed query, find similar past query, reuse response (similarity threshold)
  4. Embedding cache: hash document content → cached embedding, avoid re-embedding
  5. Retrieval cache: cache top-K Qdrant results for popular queries

Verdict

For high-volume RAG: enable all five. Each one saves a different chunk of compute.

Bottom line

Caching is the cheapest cost optimisation in AI. See prompt caching economics.

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