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Four-GPU Server Inference Architecture Patterns

Three ways to use four GPUs in one chassis, and why most teams over-invest in tensor parallel when data parallel or mixed topologies pay back better.

Four-GPU dedicated servers on our hosting are the sweet spot between single-card simplicity and rack-scale complexity. The temptation is to run one large model across all four with tensor parallelism. That is usually the wrong call. Here are the three topologies that pay back.

Topologies

Tensor Parallel Over All Four

One model, split across all four GPUs. Memory aggregate is 4x single card. Good for models that genuinely need more memory than any single GPU provides. On four RTX 4060 Tis (64 GB aggregate) you can host 70B INT4 with headroom. The catch: every forward pass now crosses three PCIe hops. Throughput at batch 1 is worse than a single 32 GB card could deliver on a smaller model.

Data Parallel – Four Independent Replicas

Load the same model on each card independently. Front with a load balancer. Four requests run in parallel. No interconnect overhead. Total aggregate throughput is strictly 4x a single card. Requires the model to fit on one GPU. For a 7-13B class model on four 5080s, this pattern crushes tensor parallel throughput by 40-60%.

Mixed TP Plus DP

Two pairs of GPUs, tensor parallel within each pair, data parallel across pairs. Good when the model needs two cards to fit but you want more throughput than a single TP-2 pair delivers. On four 5090s: two TP-2 pairs each running 70B INT4, load balanced. Higher aggregate throughput than TP-4 at the cost of running two vLLM instances.

PatternMemory AggregateThroughputComplexity
TP-4MaxLower per request, fine at high batchLow
DP-41x cardHighest, scales linearlyMedium (load balancer)
TP-2 × DP-22x cardMiddleHighest

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Which to Pick

If your model fits on one card: data parallel. Every time. Tensor parallel on a model that already fits is almost always wasted interconnect traffic.

If your model needs two cards: consider TP-2 with data parallel across two pairs.

If your model needs all four cards: you are in TP-4 territory. Also consider whether a single 6000 Pro with 96 GB would serve you better – see single 6000 Pro vs four 4060 Ti.

For specific NCCL tuning on these topologies see NCCL tuning.

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We benchmark, deploy, and optimise GPU infrastructure for AI workloads. All data in our guides comes from real-world testing on our UK-based dedicated GPU servers.

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