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Self-Hosted AI vs Azure OpenAI vs AWS Bedrock: Enterprise Comparison

The three enterprise AI deployment shapes — self-hosted dedicated, Azure OpenAI, AWS Bedrock — compared on cost, compliance, and operational complexity.

Table of Contents

  1. Comparison
  2. Verdict

Enterprise AI deployment usually narrows to three options: self-hosted dedicated, Azure OpenAI Service, or AWS Bedrock.

TL;DR

Azure OpenAI: strong compliance, GPT-4 access, Azure integration. AWS Bedrock: multi-model, AWS integration, similar enterprise features. Self-hosted: cheapest at scale, full data control, requires ops team. Most enterprises end up with hybrid.

Comparison

AspectAzure OpenAIAWS BedrockSelf-hosted
Frontier-model accessGPT-4o, o1Claude, Llama via Anthropic/MetaOpen-weight only
Cost at high volumePer-tokenPer-tokenFixed monthly
Data residencySpecific regionsSpecific regionsAnywhere
Compliance certificationsSOC2, HIPAA, etc.SOC2, HIPAA, etc.Inherits from datacenter
IntegrationAzure-nativeAWS-nativeStandalone
Operational overheadLowLowMedium
CustomisationLimited fine-tuningLimited fine-tuningFull

Verdict

  • Need GPT-4o + Azure-native: Azure OpenAI
  • Need Claude + AWS-native: AWS Bedrock
  • Cost-anchored at scale: self-hosted
  • UK/EU residency, no US transfer: self-hosted
  • Hybrid: most large enterprises

Bottom line

The three shapes coexist comfortably. See SageMaker alternatives.

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